OUR MISSION

To empower global healthcare ecosystem through innovations

Predicine is a molecular insight company developing genomic profiling tests and robust algorithms for cancer diagnostics and monitoring. Our biology-oriented approach to analyzing genomics is advancing the understanding of tumor mutational landscape.

Our passion

At Predicine, we are passionate about our people, technology, and creating a lasting impact in cancer research. 

 

People

Passionate, fearless and committed talent is our key strength. 35% of our team are PhDs.

 

Technology

We are leading the innovation in urine-based diagnostics.

 

Profound impact

Helping patients worldwide in clinical trials and easy cancer detection.

Our values and culture

Predicine is the culmination of talented people coming together to realize a shared vision. Our culture is dynamic, fast-paced, energetic and innovative. We innovate boldly and have an endless pursuit for quality. We stick by our values to carry out our important roles because we know that the work we do every day impacts real lives.

COMPANY VALUES

  • Integrity
  • Innovation
  • Quality
  • Respect
  • Courage
  • Collaboration
  • Caring
  • Communication

Leadership

Shidong Jia | CEO

Shidong Jia, MD, PhD, is the Founder and CEO of Predicine. Prior to founding Predicine, Shidong spearheaded the oncology biomarker strategies and drug & diagnostics co-development at Genentech. His previous work identified p110beta as novel drug target for PTEN-deficient tumors, a finding that laid the foundation for clinical development and testing of p110beta inhibitors in cancers. He previously held various senior research positions focusing on translational and clinical cancer research at Novartis Institutes for BioMedical Research and Harvard University. Shidong was awarded the P.A.R.T. Investigatorship Award from the Dana-Farber Cancer Institute. Shidong holds a MD and PhD from Harbin Medical University and Peking Union Medical College, and completed postdoctoral training at the Dana-Farber Cancer Institute – Harvard University.

Pan Du | President

Pan Du, PhD, is the Co-founder, President and CTO at Predicine. Pan is an expert in next-generation sequencing, bioinformatics, and oncology diagnostics. He has developed multiple widely used bioinformatics analysis software and has authored numerous publications, including several 1st authorship manuscripts that are cited over thousands times. Prior to Predicine, Pan was Principal Scientist at Roche Diagnostics and Senior Computational Biologist at Genentech. He was previously an Assistant Professor at Biomedical Informatics Center at Northwestern University. Pan holds a PhD with distinction in both Bioinformatics and Electrical Engineering from Iowa State University.

Jianjun Yu | CSO

Jianjun Yu, PhD, is the Chief Scientific Officer at Predicine. Prior to Predicine, Jianjun held various senior bioinformatics positions at Medivation, Genentech and Novartis. Jianjun is an expert in cancer genomics, target discovery & validation, clinical trial and biomarker development. He has authored numerous publications in New England Journal of Medicine and Cancer Cell, Nature, and Science. Jianjun holds a PhD in Bioinformatics from University of Michigan and a BS in Environmental Biology from Peking University.

CAREERS

Join the fight against cancer

If you enjoy challenges, collaborating with others to solve complex problems, and the chance to see your work impact the millions of lives touched by cancer, this is the place to be.

PERKS

• Healthy catered lunches
• Premium snacks and beverages
• Ample employee parking
• Happy hours and quarterly team building events 
• Close to 92 Bridge, easy access to HWY 880

Open Positions

DRY LABC++ BIOINFORMATICS ALGORITHM DEVELOPER

About Predicine

Predicine’s mission is to empower the global healthcare ecosystem through innovation. Our biology-oriented approach to analyzing cancer genomics is advancing the understanding of tumor mutational landscape and helping biopharmas accelerate the development of new cancer therapies. Predicine is the culmination of talented people coming together to fight against cancer and impacts real lives.

We are working towards detecting cancer with non-invasive means. We use DNA sequence analysis algorithms to detect rare genomic events such as SNV, structural variants (SV), methylation status, copy number variation (CNV) in the cancer cell. Here a perfect place to apply your talents to eliminate human suffering from cancer and at the same time to further your own career.

Position

A qualified candidate must have at least 5 years of experience with C++ object-oriented algorithm design and implementation.

• Deep understanding of data structures and algorithms such as suffix tree, tries, graph algorithms, De Bruijn Graph, machine learning algorithms such as Hidden Markov model, and dynamic programming.
• Clear understanding of commonly used bioinformatics algorithms such as Burrows-Wheeler transformation, sequence aligners, genome assemblers, and fast search algorithms such as Blast.
• Proficient in multi-threaded algorithm designs using the C++-11 or higher interfaces.
• Familiar with relational database, Linux/Unix, and commonly used data formats for sequencing data such as BAM.
• Basic understanding of NGS is a plus.

Responsibilities

• Design and implement multi-threaded algorithms to analyze NGS data in C++14 or up.

Who you are

In adding new members to our team, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture.

• BS or M.S. in computer science/engineering or Ph.D in bioinformatics or equivalent.
• 5+ years working experience in C++.

Predicine is an Equal Opportunity Employer

Apply Now

DRY LABBIOINFORMATICS SCIENTIST/SENIOR SCIENTIST

About Predicine

Predicine’s mission is to empower the global healthcare ecosystem through innovation. Our biology-oriented approach to analyzing cancer genomics is advancing the understanding of tumor mutational landscape and helping biopharmas accelerate the development of new cancer therapies. Predicine is the culmination of talented people coming together to fight against cancer and impacts real lives.

Position

We are seeking highly motivated scientists to lead, develop, optimize algorithms and pipelines for cancer diagnosis and early screening. This position requires an adaptable scientist to address the many demands of technology development, biomarker discovery and working with multiple stakeholders across disciplines. This position provides a broad exposure to diverse clinical and analytical problems. This individual is expected to be, or develop into, an externally recognized expert in precision diagnostics and medicine.

Responsibilities

• Lead and develop NGS analysis algorithms across a range of applications and sample types including liquid biopsies and tissue.
• Rapidly prototype or adapt bioinformatic workflows for biomarker validation, assay development, and analysis automation.
• Provide bioinformatics support in matters of equivalency testing, assay migration, analytical, and clinical validation.
• Work with wet lab scientists to build and optimize NGS procedures such as sample management, extraction, library preparation, and sequencing.

Who you are

In adding new members to our team, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture.

• Significant experience with NGS platforms and NGS analysis pipelines.
• Experience in NGS based DNA methylation and cancer early screening.
• Deep understanding in machine learning and with applications in NGS.
• Expert knowledge of R (Bioconductor) and a scripting language such as Python/Perl.
• Previous experience working in a high performance computing environment, cloud computing and Docker is a plus.
• Demonstrate initiative, strong attention to details, flexible and willing to multi-task in a rapidly evolving scientific context.
• Effective verbal and written communication skills are a must.
• PhD in bioinformatics, computer science, engineering, physics, mathematics or a related discipline.

Predicine is an Equal Opportunity Employer

Apply Now

DRY LABASSOCIATE DIRECTOR/DIRECTOR, TRANSLATIONAL MEDICINE

About Predicine

Predicine’s mission is to empower the global healthcare ecosystem through innovation. Our biology-oriented approach to analyzing cancer genomics is advancing the understanding of tumor mutational landscape and helping biopharmas accelerate the development of new cancer therapies. Predicine is the culmination of talented people coming together to fight against cancer and impacts real lives.

Position

We are seeking a seasoned scientific leader with a consistent and outstanding record of creativity and performance in cancer biology with a deep understanding of genomics and bioinformatics, evidenced by strong scientific track records in peer reviewed publications, conference presentations and patent applications. The successful candidate is expected to effectively represent the team by leading and influencing cross-functional product development teams; interacting with key partners and clinical investigators; integrating clinical and genomic data sets to support research collaborations and scientific publications and to advance biomarker discovery and company product portfolio.

Responsibilities

· Support product development and expand our product portfolio.
· Represent the translational medicine team to coordinate cross-function teams, and interact with business clients and clinical investigators.
· Drive and support publications in high quality scientific, technical or medical journals · Effectively manage internal and external scientific collaborations

Who you are

· PhD degree in a relevant scientific field (e.g. molecular biology, cancer biology, genomics, bioinformatics, or biostatistics)
· Minimum of 2+ years postdoctoral experience in translational cancer genomics research either in an academic and/or industry setting.
· Proven experience in leading and integrating high-throughput genomic data into translational or biomarker studies. Skills on genomics and bioinformatics is a plus.
· Deep knowledge and understanding of current methods used to assess tumor biology in the clinical setting, and experience with publicly available molecular oncology data sets
· Experience in clinical drug development and clinical studies is beneficial, including understanding of critical development functions, e.g., biomarker development, clinical pharmacology, regulatory, safety, operations, and biostatistics

Predicine is an Equal Opportunity Employer

Apply Now

OPERATIONSCLINICAL PROJECT MANAGER

About Predicine

Predicine’s mission is to empower the global healthcare ecosystem through innovation. Our biology-oriented approach to analyzing cancer genomics is advancing the understanding of tumor mutational landscape and helping biopharmas accelerate the development of new cancer therapies. Predicine is the culmination of talented people coming together to fight against cancer and impacts real lives.

Position

We are seeking highly motivated and talented individuals to join the biopharma business operation team to manage clinical studies, lead study activities, as well as coordinating with internal teams for project execution plans, timelines, and delivery.

Responsibilities

  • Assist in the process of contract finalization and manages all aspects of clinical study execution. Uses operational and therapeutic expertise to optimize study design, develop clinical operation plans and execution.
  • Manage biopharma customer relationships and contracts by efficient communication, excellent problem-solving skills, and on-time project delivery.
  • Assist with management and sponsor operation team for study document preparation, site training, clinical data transfer, and project execution.
  • Manage project budget, controls expenses and maintains them within financial goals;
    Assure compliance with all regulatory requirements and assists with necessary audits of data to ensure data validity. Knowledge of GCP, ICH guidelines and other regulatory requirements for clinical studies.
  • Maintain proficiency in understanding of targeted therapies in oncology and in-depth knowledge of genomic alterations in different cancers.


Who you are

In adding new members to our team, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture.

  • Bachelor’s degree (or higher) in biological science or health-related discipline.
  • 1+ years of experience (3+ years for manager position) in project management and clinical studies in Pharmaceutical, Biotech, cancer institute or CRO company.
  • Solid organizational skills and detailed oriented with an appetite to drive tasks to completion.
  • Demonstrated ability to develop positive working relationships with individuals and teams internally and externally with excellent problem-solving ability.
  • Excellent written and verbal communication skills in English.
  • Excellent knowledge of MS Office as well as project management and clinical trials software.
  • Strong understanding of GCPs, ICH, and knowledge of regulatory requirements is highly preferred.
  • Practical experience with clinical studies involving in vitro devices (IVD) or Companion Diagnostic (CDx) is a plus.
  • Maintain therapeutic knowledge through the latest research, literature, and conference.
  • Ability to work well in a rapid-pace startup environment and a matrix operating setting.
  • Ability to work independently, with minimal supervision.

Predicine is an Equal Opportunity Employer

Apply Now

WET LABRESEARCH ASSISTANT/ASSOCIATE

About Predicine

Predicine’s mission is to empower the global healthcare ecosystem through innovation. Our biology-oriented approach to analyzing cancer genomics is advancing the understanding of tumor mutational landscape and helping biopharmas accelerate the development of new cancer therapies. Predicine is the culmination of talented people coming together to fight against cancer and impacts real lives.

Position

We seek a highly motivated and talented individual that will be responsible for the development of the next-generation sequencing (NGS)-based cancer genomics workflows, including but not limited to reagent manufacturing and QC testing, guard banding, technology transferring, targeted sequencing, transcriptome sequencing, liquid biopsy assays under the supervision of the senior scientific staff. Other duties will include lab inventory and instrument maintenance.

Responsibilities

  • Execute routine lab work including material handling and downstream molecular testing, etc.
  • Reagent manufacturing and QC testing.
  • Operate and maintain instrumentation critical for lab operations including NGS, digital PCR etc.
  • Assist in preparing SOPs and reports.
  • Laboratory data entry and data processing.
  • Assist in the organization of the daily workload.
  • Assist with laboratory clean up and organization of the laboratory area.
  • Perform daily, weekly and monthly equipment maintenance as directed.
  • Maintain accurate laboratory logs and records.
  • Perform other duties as assigned.


Who you are

In adding new members to our team, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture.

  • BS with 4 years or MS with 2 years in Biology, Molecular Biology, Biochemistry or a closely related field.
  • Solid background in molecular biology or biochemistry, good general laboratory techniques, and documentation skills.
  • The ability to prioritize and complete tasks and advance projects.
  • The ability to interact adaptably with scientists and non-scientists from various disciplines.
  • Excellent written and verbal communication skills.
  • A willingness to work hard and be creative in a fast-paced environment.
  • Experience with automation is a plus.


Predicine is an Equal Opportunity Employer

Apply Now

WET LABCLINICAL LABORATORY SCIENTIST (CLS) , CLINICAL MOLECULAR DIAGNOSTICS

About Predicine

Predicine’s mission is to empower the global healthcare ecosystem through innovation. Our biology-oriented approach to analyzing cancer genomics is advancing the understanding of tumor mutational landscape and helping biopharmas accelerate the development of new cancer therapies. Predicine is the culmination of talented people coming together to fight against cancer and impacts real lives.

Position

We are seeking highly motivated and talented individuals to join as a CLS, under the oversight of the Clinical Laboratory Director in our Hayward, CA CAP-accredited and CLIA-certified laboratory. This person will provides technical expertise in a CLIA laboratory providing molecular testing and assays for the diagnosis of genetic diseases, cancer, companion diagnostic tests, and biomarkers for disease monitoring and stratification.

Responsibilities

  • Perform high complex molecular genetic tests including DNA/RNA extraction, PCR, and Next Generation Sequencing on patients’ specimens including all steps from sample processing to result reporting as per the company SOPs.
  • Bring forth the specialized scientific and technical knowledge essential to perform lab testing.
  • Successfully complete all proficiency testing prior to submission to the Laboratory Director.
  • Maintain pertinent records according to the Quality Management plan to ensure compliance with all local, state and federal regulations.
  • Assist in assay validation studies of lab developed tests with the approval of the Laboratory Director.
  • Demonstrate the ability to maintain competency and take on training responsibilities as needed.
  • Perform troubleshooting, maintenance, and problem resolution.
  • May assist with duplicate operations in Shanghai as needed.
  • Perform other duties as assigned and assist others as time allows.


Who you are

In adding new members to our team, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture. Because we know that people are critical to our success in bringing precision diagnostics and medicines to patients, we are dedicated to creating a great place to work and to providing people with programs, services and benefits that allow them to bring the best to the business and to their personal and professional growth.

  • Current California Clinical Laboratory Scientist License (CLS) generalist or Clinical Genetic Molecular Biologist Scientist License (CGMBS).
  • Prior experience with PCR based and/ or next-generation sequencing (NGS) methods and data analysis preferred.
  • General office and laboratory conditions, mobility to work in a typical clinical laboratory setting using standard equipment.
    Able to lift up to 20 lbs on an occasional basis.
  • Repetitive manual pipetting may be necessary.
  • Occasional International travel may be required.

Predicine is an Equal Opportunity Employer

Apply Now

SALESDIRECTOR, BUSINESS DEVELOPMENT

Who We Are

Predicine is a Silicon Valley-based global precision medicine company that is committed to developing the first- and best-in-class liquid biopsy cancer diagnostics and precision medicine portfolio to address the unmet medical needs in global drug development. We aim to provide innovative blood- and urine-based molecular diagnostic tests to enable precision medicine. Predicine’s liquid biopsy platform and molecular insight solutions enable biopharma companies to accelerate drug development and expand discovery in oncology. We partner with the top 10 leading global biopharma companies to support biomarker-driven clinical trials in US, EU, APAC including China. At Predicine, we believe people are our most important asset and we are dedicated to creating a great place to work. We value a culture of creativity, integrity, responsibility, productivity, and teamwork.

Location USA

Position

In this role, you will be responsible for leading the business development for Predicine’s portfolio of biomarker solutions including NGS liquid biopsy genomic assays across Predicine’s biopharma client base. You will gather clients’ biomarker-driven trial needs, help educate and build relationships/partnerships in support of clients’ clinical trial programs through Predicine’s biomarker solution portfolio.

Collaboration is a key success factor. You will work cross-functionally with internal stakeholders. As a key member of Predicine’s global Business Development team, you will provide the voice of customer, help shape the product strategy to meet biopharma customer need, and contribute to other strategic projects within the BD group and across the entire global organization.

‪You must be able to operate in a fast-paced organization and have extremely high standards and accountability on quality of deliverables.‬‬‬ This is an exciting opportunity to join a fast-growing startup to accelerate your growth, contribute, and make an immediate impact on cancer care worldwide.‬‬‬‬‬‬‬

Responsibilities

• Identify areas of alignment between Predicine’s assay portfolio, oncology development and commercial portfolio of your biopharma accounts to generate new business opportunities that contribute to the biopharma group goals.
• Interact with internal subject matter experts at biopharma companies to develop and execute partnerships within the organization and execute business development activities for your accounts.
• Develop relationships with clients, identify, and support additional value-creation opportunities across the bioparma solutions portfolio.
• Drive progress for defined partner strategies, proactively raise issues, propose and execute solutions.
• Contribute to the overall development of the biopharma solutions portfolio and support strategic transactions beyond the direct biopharma business line.
• Provide exceptional leadership for translating innovative liquid biopsy technology to advance clinical biomarker assessment in personalized cancer care and oncology clinical trials
• Provide exceptional business leadership within company, particularly to groups of other functions in product development.
• Participate in, or lead, disease focused translational biomarker product development. Support scientific and technical innovation collaboratively with other members of the company.
• Prepare high quality scientific, technical or medical materials.
• Represent the company externally through presentations at key national/international meetings. Interact with key partners.
• Participate and thrive in a fast-paced, interactive, team-oriented culture.

Who you are

In adding new members to our team, we look for people who are inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture. Because we know that people are critical to our success in business, we are dedicated to creating a great place to work and to providing people with programs, services and benefits that allow them to bring the best to the business and to their personal and professional growth.
‪‬‬‬‬‬‬‬‬‬‬‬
• Degree in life sciences preferred, BA, MS, PhD, or MD degree in a relevant scientific field (e.g. pathology, molecular biology, cancer genetics, cancer biology, molecular oncology).
• Minimum of 5 years of experience in sales, marketing, business development, and basic, clinical or translational research either in an academic and/or biopharma industry setting; experience in biotech/pharmaceuticals or clinical diagnostics is preferred
• Experience in clinical practice or drug development is beneficial, including basic or advanced understanding of critical development functions, e.g. oncology biomarker development, clinical trials, targeted therapy, immune-oncology, etc.
• Enthusiastic, confident, and dedicated to work in a cross-functional team setting involving R&D, product development, finance, legal, marketing, and other groups.
• Outstanding presentation and communication skills.
• Ability to lead, influence, and motivate others.
• Able to distill complex issues and clearly articulate solutions.
• Ability to demonstrate effectiveness and growth in a fast-paced and dynamic environment.
• Travel required.

Predicine is an Equal Opportunity Employer

Apply Now

WET LABSENIOR SCIENTIST/SCIENTIST/ASSOCIATE DIRECTOR

About Predicine

Predicine’s mission is to empower the global healthcare ecosystem through innovation. Our biology-oriented approach to analyzing cancer genomics is advancing the understanding of tumor mutational landscape and helping biopharmas accelerate the development of new cancer therapies. Predicine is the culmination of talented people coming together to fight against cancer and impacts real lives.

The Position

We seek a highly motivated and talented scientist to build, optimize and maintain computational NGS workflows. This position requires an adaptable scientist to address the many demands of technology development, biomarker validation, software prototyping and working with multiple stakeholders across disciplines. This position provides broad exposure to diverse clinical and analytical problems. This individual is expected to be, or develop into, externally recognized expert in precision diagnostics and medicine.

Responsibilities

  • Drive scientific and technical innovation by developing and executing on disease-focused, fit-for-purpose NGS assays.
    Perform hands-on tasks to design, optimize, validate ad implement targeted sequencing panels to advance clinical biomarker assessment.
  • Effectively manage team works, prepare SOPs and reports.
  • Thrive in a highly interactive, fast-paced and dynamic team environment, and actively participate in internal/external collaboration.


Who you are

In adding new members to our team, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture.

  • PhD degree in life sciences with >3 years of work experience in basic or cancer related research field either in an academic or industry laboratory setting.
  • Deep knowledge and solid hands on experience in the NGS assay development (sample preparation, library construction, target sequencing, especially methylation sequencing).
  • Ability to plan, execute, analyze and troubleshoot experiments independently.
  • Ability to lead, influence and motivate others and to distill complex issues and clearly articulate solutions.
  • Self-starter, proactive, and dedicated. Outstanding organizational, time management, and people interaction skills.
  • Demonstrate initiative, strong attention to details, flexible and willing to multi-task in a rapidly evolving scientific context.
  • Effective verbal and written communication skills are a must.
  • International travels required based on project need.

Predicine is an Equal Opportunity Employer

Apply Now

OPERATIONSCLINICAL PROJECT MANAGER

We are seeking highly motivated and talented individuals to join the biopharma business operation team to manage clinical studies, lead study activities, as well as coordinating with internal teams for project execution plans, timelines and delivery.

You are expected to:

Assists in the process of contract finalization and manages all aspects of clinical study execution. Uses operational and therapeutics expertise to optimize study design, develop clinical operation plans and execution.
Manages biopharma customer relationships and contracts by efficient communication, excellent problem solving skills and on-time project delivery.
Assists with management and sponsor operation team for study document preparation, site training, clinical data transfer, and project execution.
Manages project budget, controls expenses and maintains them within financial goals;
Assures compliance with all regulatory requirements and assists with necessary audits of data to ensure data validity. Knowledge of GCP, ICH guidelines and other regulatory requirements for clinical studies.
Maintains proficiency in understanding of targeted therapies in oncology and an in-depth knowledge of genomic alterations in different cancers.

Qualifications

Bachelor’s degree (or higher) in biological science or health-related discipline
1+ year of experience (3+ years for manager position) in project management and clinical studies in Pharmaceutical, Biotech, cancer institute or CRO company.
Solid organizational skills and detailed oriented with an appetite to drive tasks to completion
Demonstrated ability to develop positive working relationships with individuals and teams internally and externally with excellent problem solving ability.
Excellent written and verbal communication skills in English.
Excellent knowledge of MS Office as well as project management and clinical trials software
Strong understanding of GCPs, ICH, and knowledge of regulatory requirements is highly preferred.
Practical experience with clinical studies involving in vitro devices (IVD) or Companion Diagnostic (CDx) is a plus
Maintain therapeutic knowledge through the latest research, literature, and conference.
Ability to work well in a rapid-pace startup environment and a matrix operating setting
Ability to work independently, with minimal supervision

WET LABSENIOR SCIENTIST/SCIENTIST/ASSOCIATE DIRECTOR

We seek a highly motivated and talented scientist to build, optimize and maintain computational NGS workflows. This position requires an adaptable scientist to address the many demands of technology development, biomarker validation, software prototyping and working with multiple stakeholders across disciplines. This position provides broad exposure to diverse clinical and analytical problems. This individual is expected to be, or develop into, externally recognized expert in precision diagnostics and medicine.

Responsibilities

Drive scientific and technical innovation by developing and executing on disease-focused, fit-for-purpose NGS assays.
Perform hands-on tasks to design, optimize, validate ad implement targeted sequencing panels to advance clinical biomarker assessment.
Effectively manage team works, prepare SOPs and reports.
Thrive in a highly interactive, fast-paced and dynamic team environment, and actively participate in internal/external collaboration.

Who you are

In adding new members to our team, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture.

PhD degree in life sciences with >3 years of work experience in basic or cancer related research field either in an academic or industry laboratory setting.
Deep knowledge and solid hands on experience in the NGS assay development (sample preparation, library construction, target sequencing, especially methylation sequencing).
Ability to plan, execute, analyze and troubleshoot experiments independently.
Ability to lead, influence and motivate others and to distill complex issues and clearly articulate solutions.
Self-starter, proactive, and dedicated. Outstanding organizational, time management, and people interaction skills
Demonstrate initiative, strong attention to details, flexible and willing to multi-task in a rapidly evolving scientific context
Effective verbal and written communication skills are a must
International travels required based on project need

WET LABRESEARCH ASSISTANT

We seek a highly motivated and talented scientist to build, optimize and maintain computational NGS workflows. This position requires an adaptable scientist to address the many demands of technology development, biomarker validation, software prototyping and working with multiple stakeholders across disciplines. This position provides broad exposure to diverse clinical and analytical problems. This individual is expected to be, or develop into, externally recognized expert in precision diagnostics and medicine.

Responsibilities

Assist in NGS workflows including nucleic acid extraction from various tissue specimens (cell line, blood, FFPE), Illumina and other-based library construction and enrichment.
Provide support for the operation and maintenance of instrumentation critical for NGS workflows (qPCR, Bioanalyzer, Qubit, plate readers and sequencer) a plus.
CLIA experience is a plus.
Assist in preparing SOPs and reports

Who you are

In adding new members to our team, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture.

BS or MS in Biology, Molecular Biology, Biochemistry or a closely related field.
Background in molecular biology or biochemistry, general laboratory techniques and procedures (PCR, qPCR, nucleic acid purification).
The ability to prioritize and complete tasks and advance projects.
The ability to interact adaptably with scientists and non-scientists from various disciplines.
Excellent written and verbal communication skills.
A willingness to work hard and be creative in a fast-paced environment.

WET LABCLINICAL LABORATORY SCIENTIST (CLS) , CLINICAL MOLECULAR DIAGNOSTICS

We are seeking highly motivated and talented individuals to join as a CLS, under the oversight of the Clinical Laboratory Director in our Hayward, CA CAP-accredited and CLIA-certified laboratory. This person will provides technical expertise in a CLIA laboratory providing molecular testing and assays for the diagnosis of genetic diseases, cancer, companion diagnostic tests, and biomarkers for disease monitoring and stratification.

Responsibilities:

As CLS of the Clinical Laboratory, you are expected to:
Perform high complex molecular genetic tests including DNA/RNA extraction, PCR, and Next Generation Sequencing on patients’ specimens including all steps from sample processing to result reporting as per the company SOPs
Bring forth the specialized scientific and technical knowledge essential to perform lab testing.
Successfully complete all proficiency testing prior to submission to the Laboratory Director.
Maintain pertinent records according to the Quality Management plan to ensure compliance with all local, state and federal regulations.
Assist in assay validation studies of lab developed tests with the approval of the Laboratory Director.
Demonstrate the ability to maintain competency and take on training responsibilities as needed.
Perform troubleshooting, maintenance, and problem resolution.
May assist with duplicate operations in Shanghai as needed.
Perform other duties as assigned and assist others as time allows.

Who you are:

In adding new members to our team, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture. Because we know that people are critical to our success in bringing precision diagnostics and medicines to patients, we are dedicated to creating a great place to work and to providing people with programs, services and benefits that allow them to bring the best to the business and to their personal and professional growth.
Current California Clinical Laboratory Scientist License (CLS) generalist or Clinical Genetic Molecular Biologist Scientist License (CGMBS).
Prior experience with PCR based and/ or next generation sequencing (NGS) methods and data analysis preferred.
General office and laboratory conditions, mobility to work in a typical clinical laboratory setting using standard equipment.
Able to lift up to 20 lbs on an occasional basis.
Repetitive manual pipetting may be necessary.
Occasional International travel may be required.

DRY LABC++ BIOINFORMATICS ALGORITHM DEVELOPER

About Predicine

Predicine’s mission is to empower the global healthcare ecosystem through innovation. Our biology-oriented approach to analyzing cancer genomics is advancing the understanding of tumor mutational landscape and helping biopharmas accelerate the development of new cancer therapies. Predicine is the culmination of talented people coming together to fight against cancer and impacts real lives.

We are working towards detecting cancer with non-invasive means. We use DNA sequence analysis algorithms to detect rare genomic events such as SNV, structural variants (SV), methylation status, copy number variation (CNV) in the cancer cell. Here a perfect place to apply your talents to eliminate human suffering from cancer and at the same time to further your own career.

Position

A qualified candidate must have at least 5 years of experience with C++ object-oriented algorithm design and implementation.

• Deep understanding of data structures and algorithms such as suffix tree, tries, graph algorithms, De Bruijn Graph, machine learning algorithms such as Hidden Markov model, and dynamic programming.
• Clear understanding of commonly used bioinformatics algorithms such as Burrows-Wheeler transformation, sequence aligners, genome assemblers, and fast search algorithms such as Blast.
• Proficient in multi-threaded algorithm designs using the C++-11 or higher interfaces.
• Familiar with relational database, Linux/Unix, and commonly used data formats for sequencing data such as BAM.
• Basic understanding of NGS is a plus.

Responsibilities

• Design and implement multi-threaded algorithms to analyze NGS data in C++14 or up.

Who you are

In adding new members to our team, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture.

• BS or M.S. in computer science/engineering or Ph.D in bioinformatics or equivalent.
• 5+ years working experience in C++.

Predicine is an Equal Opportunity Employer

Apply Now

DRY LABBIOINFORMATICS SCIENTIST/SENIOR SCIENTIST

About Predicine

Predicine’s mission is to empower the global healthcare ecosystem through innovation. Our biology-oriented approach to analyzing cancer genomics is advancing the understanding of tumor mutational landscape and helping biopharmas accelerate the development of new cancer therapies. Predicine is the culmination of talented people coming together to fight against cancer and impacts real lives.

Position

We are seeking a highly motivated scientist to lead, develop, optimize algorithms and pipelines for cancer diagnosis and early screening. This position requires an adaptable scientist to address the many demands of technology development, biomarker discovery and working with multiple stakeholders across disciplines. This position provides a broad exposure to diverse clinical and analytical problems. This individual is expected to be, or develop into, an externally recognized expert in precision diagnostics and medicine.

Responsibilities

• Lead and develop NGS analysis algorithms across a range of applications and sample types including liquid biopsies and tissue.
• Rapidly prototype or adapt bioinformatic workflows for biomarker validation, assay development, and analysis automation.
• Provide bioinformatics support in matters of equivalency testing, assay migration, analytical, and clinical validation.
• Work with wet lab scientists to build and optimize NGS procedures such as sample management, extraction, library preparation, and sequencing.

Who you are

In adding new members to our team, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture.

• Significant experience with NGS platforms and NGS analysis pipelines.
• Experience in NGS based DNA methylation and cancer early screening.
• Deep understanding in machine learning and with applications in NGS.
• Expert knowledge of R (Bioconductor) and a scripting language such as Python/Perl.
• Previous experience working in a high performance computing environment, cloud computing and Docker is a plus.
• Demonstrate initiative, strong attention to details, flexible and willing to multi-task in a rapidly evolving scientific context.
• Effective verbal and written communication skills are a must.
• PhD in bioinformatics, computer science, engineering, physics, mathematics or a related discipline.

Predicine is an Equal Opportunity Employer

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DRY LABASSOCIATE DIRECTOR/DIRECTOR, TRANSLATIONAL MEDICINE

About Predicine

Predicine’s mission is to empower the global healthcare ecosystem through innovation. Our biology-oriented approach to analyzing cancer genomics is advancing the understanding of tumor mutational landscape and helping biopharmas accelerate the development of new cancer therapies. Predicine is the culmination of talented people coming together to fight against cancer and impacts real lives.

Position

We are seeking a seasoned scientific leader with a consistent and outstanding record of creativity and performance in cancer biology with a deep understanding of genomics and bioinformatics, evidenced by strong scientific track records in peer reviewed publications, conference presentations and patent applications. The successful candidate is expected to effectively represent the team by leading and influencing cross-functional product development teams; interacting with key partners and clinical investigators; integrating clinical and genomic data sets to support research collaborations and scientific publications and to advance biomarker discovery and company product portfolio.

Responsibilities

· Support product development and expand our product portfolio.
· Represent the translational medicine team to coordinate cross-function teams, and interact with business clients and clinical investigators.
· Drive and support publications in high quality scientific, technical or medical journals · Effectively manage internal and external scientific collaborations

Who you are

· PhD degree in a relevant scientific field (e.g. molecular biology, cancer biology, genomics, bioinformatics, or biostatistics)
· Minimum of 2+ years postdoctoral experience in translational cancer genomics research either in an academic and/or industry setting.
· Proven experience in leading and integrating high-throughput genomic data into translational or biomarker studies. Skills on genomics and bioinformatics is a plus.
· Deep knowledge and understanding of current methods used to assess tumor biology in the clinical setting, and experience with publicly available molecular oncology data sets
· Experience in clinical drug development and clinical studies is beneficial, including understanding of critical development functions, e.g., biomarker development, clinical pharmacology, regulatory, safety, operations, and biostatistics

Predicine is an Equal Opportunity Employer

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SalesDIRECTOR, BUSINESS DEVELOPMENT

Who We Are

Predicine is a Silicon Valley-based global precision medicine company that is committed to developing the first- and best-in-class liquid biopsy cancer diagnostics and precision medicine portfolio to address the unmet medical needs in global drug development. We aim to provide innovative blood- and urine-based molecular diagnostic tests to enable precision medicine. Predicine’s liquid biopsy platform and molecular insight solutions enable biopharma companies to accelerate drug development and expand discovery in oncology. We partner with the top 10 leading global biopharma companies to support biomarker-driven clinical trials in US, EU, APAC including China. At Predicine, we believe people are our most important asset and we are dedicated to creating a great place to work. We value a culture of creativity, integrity, responsibility, productivity, and teamwork.

Location USA

Position

In this role, you will be responsible for leading the business development for Predicine’s portfolio of biomarker solutions including NGS liquid biopsy genomic assays across Predicine’s biopharma client base. You will gather clients’ biomarker-driven trial needs, help educate and build relationships/partnerships in support of clients’ clinical trial programs through Predicine’s biomarker solution portfolio.

Collaboration is a key success factor. You will work cross-functionally with internal stakeholders. As a key member of Predicine’s global Business Development team, you will provide the voice of customer, help shape the product strategy to meet biopharma customer need, and contribute to other strategic projects within the BD group and across the entire global organization.

‪You must be able to operate in a fast-paced organization and have extremely high standards and accountability on quality of deliverables.‬‬‬ This is an exciting opportunity to join a fast-growing startup to accelerate your growth, contribute, and make an immediate impact on cancer care worldwide.‬‬‬‬‬‬‬

Responsibilities

• Identify areas of alignment between Predicine’s assay portfolio, oncology development and commercial portfolio of your biopharma accounts to generate new business opportunities that contribute to the biopharma group goals.
• Interact with internal subject matter experts at biopharma companies to develop and execute partnerships within the organization and execute business development activities for your accounts.
• Develop relationships with clients, identify, and support additional value-creation opportunities across the bioparma solutions portfolio.
• Drive progress for defined partner strategies, proactively raise issues, propose and execute solutions.
• Contribute to the overall development of the biopharma solutions portfolio and support strategic transactions beyond the direct biopharma business line.
• Provide exceptional leadership for translating innovative liquid biopsy technology to advance clinical biomarker assessment in personalized cancer care and oncology clinical trials
• Provide exceptional business leadership within company, particularly to groups of other functions in product development.
• Participate in, or lead, disease focused translational biomarker product development. Support scientific and technical innovation collaboratively with other members of the company.
• Prepare high quality scientific, technical or medical materials.
• Represent the company externally through presentations at key national/international meetings. Interact with key partners.
• Participate and thrive in a fast-paced, interactive, team-oriented culture.

Who you are

In adding new members to our team, we look for people who are inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture. Because we know that people are critical to our success in business, we are dedicated to creating a great place to work and to providing people with programs, services and benefits that allow them to bring the best to the business and to their personal and professional growth.
‪‬‬‬‬‬‬‬‬‬‬‬
• Degree in life sciences preferred, BA, MS, PhD, or MD degree in a relevant scientific field (e.g. pathology, molecular biology, cancer genetics, cancer biology, molecular oncology).
• Minimum of 5 years of experience in sales, marketing, business development, and basic, clinical or translational research either in an academic and/or biopharma industry setting; experience in biotech/pharmaceuticals or clinical diagnostics is preferred
• Experience in clinical practice or drug development is beneficial, including basic or advanced understanding of critical development functions, e.g. oncology biomarker development, clinical trials, targeted therapy, immune-oncology, etc.
• Enthusiastic, confident, and dedicated to work in a cross-functional team setting involving R&D, product development, finance, legal, marketing, and other groups.
• Outstanding presentation and communication skills.
• Ability to lead, influence, and motivate others.
• Able to distill complex issues and clearly articulate solutions.
• Ability to demonstrate effectiveness and growth in a fast-paced and dynamic environment.
• Travel required.

Predicine is an Equal Opportunity Employer

Apply Now

News & Events

LABORATORY

Our molecular genetics lab

We have a CAP-accredited and CLIA-certified laboratory in Hayward, California that uses the most cutting-edge technologies and instruments including Illumina MiniSeq™, Illumina NextSeq™, and Illumina NovaSeq™ 6000 System.   Our high-caliber laboratory staff bring a wealth of sequencing and sample expertise to ensure accuracy and reliability of results.

 

Predicine’s licenses and accreditations:

  • CAP Accreditation: 8169662
  • CLIA Certificate: 05D2148483
  • State of Maryland: 2906
  • State of Pennsylvania: 36601
  • State of Rhode Island: LCO001259
  • State of California: CFD00351747

 

Contact us

If you have any questions or need assistance, our customer support team is on-hand to help.

ADDRESS

3555 Arden Road
Hayward, CA 94545, USA

ADDRESS

1698 Wangyuan Road, Building 11
Shanghai, 201499, China

Get in touch

We would love to hear from you. Please use the form below to submit your questions, comments, or inquries about potential partnerships.